unsupported
some positive reports / partially supported
implicit support
explicit support
DAWs
Adobe Audition
“macOS Monterey (version 12) or later” and it’s also in the list of compatible Adobe software.
Audacity
“MacOS 12 & 13, with OS X versions since 10.9 believed to still work”
Hindenburg PRO
“macOS v11 to macOS 15, Sequoia” are compatible
ProTools
Pro Tools Operating System Compatibility Chart states that “Pro Tools 2024.10 is supported with macOS Sequoia. Please be aware that there are some known issues”.
Reaper
“REAPER supports macOS 10.5* to macOS 14.”
Plugins
Eventide
“All Eventide and Newfangled Audio plug-ins are compatible with macOS 15 Sequoia”
Izotope
A long list of Isotope products are compatible.
Waves
Version 15 plugins support MacOS 15
Other Software
BlackHole
“Compatible with macOS 10.10 Yosemite and newer.”
Descript
“macOS 11.0 (Big Sur) or later”
Dipper
Røde Central
Røde Connect
Rogue Amoeba
“All Rogue Amoeba Apps Support MacOS 15 (Sequoia)”